5-(4-Fluoro-3-Methoxyphenyl)nicotinic acid
5-(4-Fluoro-3-methoxyphenyl)nicotinic acid
CAS: 1261934-09-1
Molecular Formula: C13H10FNO3
5-(4-Fluoro-3-Methoxyphenyl)nicotinic acid - Names and Identifiers
5-(4-Fluoro-3-Methoxyphenyl)nicotinic acid - Physico-chemical Properties
| Molecular Formula | C13H10FNO3 |
| Molar Mass | 247.22 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD18317538 |
5-(4-Fluoro-3-Methoxyphenyl)nicotinic acid - Introduction
5-(4-Fluoro-3-methoxyphenyl)nicotinic acid is an organic compound also known as 4-fluoro-3-methoxyphenylnicotinic acid.
Nature:
-Appearance: Colorless crystalline powder
-Molecular formula: C13H10FNO3
-Molecular weight: 249.22g/mol
-Melting point: 135-138°C
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide and ammonia, insoluble in water.
Use:
-Chemical intermediates: can be used to synthesize drugs and other organic compounds.
-Drug research: It has certain biological activity and may be used in drug research and development.
Preparation Method:
The synthesis of 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid can be achieved through the following steps:
1. First, the para-methoxyphenol is reacted with 4-fluorobenzene chloride to generate 4-fluoro -3-methoxybenzene.
2. Esterification of 4-fluoro-3-methoxybenzene with nicotinic acid to generate 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid.
Safety Information:
- 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid has limited information on toxicity and harmfulness, so corresponding safety precautions should be taken during use and handling.
-Avoid contact with eyes, skin and respiratory tract, and maintain good ventilation.
-Observe relevant safety procedures during use and storage, and use personal protective equipment, such as gloves and protective glasses.
Nature:
-Appearance: Colorless crystalline powder
-Molecular formula: C13H10FNO3
-Molecular weight: 249.22g/mol
-Melting point: 135-138°C
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide and ammonia, insoluble in water.
Use:
-Chemical intermediates: can be used to synthesize drugs and other organic compounds.
-Drug research: It has certain biological activity and may be used in drug research and development.
Preparation Method:
The synthesis of 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid can be achieved through the following steps:
1. First, the para-methoxyphenol is reacted with 4-fluorobenzene chloride to generate 4-fluoro -3-methoxybenzene.
2. Esterification of 4-fluoro-3-methoxybenzene with nicotinic acid to generate 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid.
Safety Information:
- 5-(4-Fluoro-3-methoxyphenyl)nicotinic acid has limited information on toxicity and harmfulness, so corresponding safety precautions should be taken during use and handling.
-Avoid contact with eyes, skin and respiratory tract, and maintain good ventilation.
-Observe relevant safety procedures during use and storage, and use personal protective equipment, such as gloves and protective glasses.
Last Update：2024-04-09 21:01:54
